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Zoloft (Pfizer, New York, NY, USA) contains sertraline as an active component and belongs to the pharmacological group of antidepressants. The medication eliminates anxiety, manic conditions, panic, social anxiety disorders, and other manifestations of mental disorders. Zoloft is indicated for use by adults, children, and adolescents aged between 13 years and 17 years alike to treat obsessive-compulsive disorders.

Use of the drug leads to an overdose only when used with other medicines at the same time. The antidepressant drug category has several analogs with the same active substances and a number of drugs that are similar in effect.

Composition and form of release

The medication is made in tablet form. The active ingredient content is either 50 mg or 100 mg. The active substance of the drug is a sertraline component in the form of hydrochloride.

Indications for use

Indications for the use of Zoloft include various forms of depressive states and social phobia. A doctor may also prescribe this antidepressant to children and adolescents with obsessive-compulsive disorders.

The drug eliminates the signs of panic disorders, such as anxiety and the fear of loneliness, death, or visits to crowded places. Zoloft is also used for treating post-traumatic stress disorder.

Based on the responses of patients using the drug, its high efficiency has been noted. One disadvantage is the length of time of treatment: marked improvement after administration is slow to appear.

Dosage

Zoloft tablets are taken regardless of food intake. The multiplicity of admission is one time per day in the morning or evening. Dosage can vary depending on the purpose of usage: for example, for obsessive-compulsive disorders and depression, the dose starts at 50 mg per day.

For the treatment of social phobia, panic disorders, and post-traumatic stress conditions, admission begins with 25 mg per day, increasing the dose per week by 25 mg. Such a therapeutic regimen reduces the incidence of undesirable effects, which are particularly characteristic of panic conditions.

If the effect of the drug is expressed implicitly, then the dose is increased from 50 mg to 200 mg per day, but with a frequency of once every seven days. Initial results of using the medication may be noted at one week after the start of the treatment course, but the full effect is not achieved until after one month of use. In obsessive-compulsive disorders, the result may take longer to identify.

Contraindications

Antidepressants are not prescribed for patients who have not reached the age of six years and individuals with a high degree of sensitivity to the active component.

Other contraindications for use include:

  • Breastfeeding
  • Pregnancy
  • Treatment with pimozide
  • Therapy with MAO inhibitors

Side effects

This medication has been associated with side effects that impact the functions of the digestive tract, which generally manifest themselves as dyspeptic disorders, as follows:

  • Pancreatitis
  • Flatulence
  • Abdominal pain
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea