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Amoxicillin belongs to the penicillin drug group demonstrating an extended duration of action.
Amoxicillin is considered a semi-synthetic drug. In contrast to natural antibiotics, this drug demonstrates a more pronounced antibacterial effect due to the modification of penicillin molecules in the laboratory.
The active substance contained within this drug is amoxicillin trihydrate. The primary effect of this drug ingredient is to penetrate bacterial colonies and inhibit the formation of new cell membranes. An important advantage of this drug is that Amoxicillin is able to suppress the multiplication of pathogenic microorganisms without exerting a destructive effect on the body.
Amoxicillin is active against most harmful bacteria including both gram-positive and gram-negative strains. This drug also retains its activity even in an acidic environment. Within 1 hour after oral administration of Amoxicillin, all tissues of the body can be found with high drug concentrations.
Amoxicillin provides excellent results for the treatment of diseases involving:
- upper respiratory tract, including laryngitis, sinusitis, and tracheitis
- pneumonia and/or bronchitis
- kidney and genital infections, including pyelonephritis, glomerulonephritis, cystitis, urethritis, gonorrhea, and/or prostatitis
- gastritis and/or peptic ulcer
- erysipelas of the skin
- dysentery and/or salmonellosis
- meningitis, myocarditis, and/or endocarditis
Adults, as well as children over the age of ten, can be prescribed one 500 mg tablet (or two 250 mg tablets) to be taken three times per day. For children 5 to 10 years of age, the recommended dosage is 250 mg to be taken in the morning, lunchtime, and evening. A typical course of treatment with this drug is 10 days.
Amoxicillin should be taken following a meal with plenty of alkaline mineral water or milk.
If a patient is diagnosed with acute gonorrhea, treatment involves a single-time use of six 500 mg tablets. For acute intestinal infections, Amoxicillin should be taken in the amount of 4 tablets three times daily over the course of 5 days.
The main side effects of amoxicillin involve:
- development of allergic reactions
- irritation of the gastrointestinal (GI) tract
With respect to allergic reactions, this can manifest in the form of skin rashes, difficulty breathing, and/or swelling of the face and limbs. In contrast, side effects associated with the GI tract present as diarrhea, abdominal pain, nausea, and/or decreased appetite.
When pregnant, Amoxicillin should be taken caution and under constant supervision of a doctor.
Amoxicillin should not be taken with alcohol. This combination can cause a violent allergic reaction.